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2003 September, Jhumpa Lahiri, chapter 1, in The Namesake, New York, N.Y.: Mariner Books, published 2004, ISBN, page 17: [...] Ashoke was still reading at two-thirty in the morning, one of the few passengers on the train who was awake, when the locomotive engine and seven bogies derailed from the broad-gauge line

Then in 1950, two landmark studies one by Ernst Wynder and Evarts Graham in the United States, another by Richard Doll and Austin Bradford Hill in Britain provided strong statistical links between cigarettes and lung cancer